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ViraVector

Production of viral vectors (adeno-associated virus and lentiviral vectors) and non-viral vectors (exosomes and vexosomes); Isolation of extracellular vesicles from biological fluids; Engineering of viral vectors; Gene transfer studies in cells and animals

Websitehttps://www.cibb.uc.pt/scientific-platforms/viravector/
E-mailrui.nobre@cnc.uc.pt

7 available services

Consultancy & Support

 Plasmid design; Cloning; Vector design and engineering; Purification processes; Chromatography; Clean rooms; Instrumentation; Gene therapy; Cell models; Animal models; Disease models; Assays; Preclinical studies; Data analysis; Others.
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Isolation of Extracellular Vesicles / Exosomes from biological fluids

 Isolation of Extracellular Vesicles / Exosomes from diferent biological fluids
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Production and Purification of Adeno-associated viral vectors (AAVs)

 Production of highly pure AAVs (AAV1, AAV2, AAV5, AAV6, AAV8, AAV9, PhP.eB) using an optimized platform based on high performance liquid chromatography.
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Production and Purification of Lentiviral vectors (LVs)

 Production of highly pure lentiviral vectors using an optimized platform.
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Production and Purification of modified exosomes

 Production of modified exosomes - extracelular vesicles (EVs)
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Titration and Characterization of NON-VIRAL PARTICLES

 Measurement and Characterization of non-viral vectors (Extracellular vesicles / Exosomes) in various types of samples using a diferent set of assays.
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Titration and Characterization of VIRAL particles

 Measurement of viral vector titer (AAV, LV, vesoxome) in various types of samples using a diferent set of assays.
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